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TrichoGene-MRT predicts success of hair loss treatment response with Minoxidil.



One of the top queries from people looking into how to regrow thinning hair is, “does hair loss treatment work?” what can never guarantee Whilst results, given everyone responds uniquely to medication, certain levels of regrowth and stabilization can be estimated on a case-by-case basis by experienced professionals, up to a point.

 Now, the new test in the Indian market can predict how well men and women with androgenetic alopecia will respond to the clinically-proven treatment, Minoxidil. TrichoGene India introduced the Minoxidil Response DNA Test (MRT), founded by two young entrepreneurs, Dr M Sai Babu and Mohd Rizwan Younus. MRT is based on pharmacogenetics, where the SULT1A1 gene will be analyzed to determine whether a sufficient quantity of sulphotransferase enzyme is present or not to increase the activity of Minoxidil.

What Is the Minoxidil Mechanism of Action for Hair Growth?

Minoxidil is one of the most commonly used medications for men and women experiencing hair loss. You may be familiar with Minoxidil as the active ingredient inside of the brand-name medication Rogaine. But, whether you opt for the brand name or a generic Minoxidil, you should experience the same results.

People using Minoxidil topically on the scalp may notice their hair growing faster, thicker, and denser. It usually takes a few months to start noticing the positive effects of treatment. Also, there may be a shedding period at the beginning of treatment due to the hairs in the resting (telogen) hair phase being shifted over in bulk to the growing (anagen) hair phase. Ultimately, this is a good thing for hair growth.

Minoxidil was initially used as an oral medication to help with high blood pressure. And we know that it helps with high blood pressure by dilating vessels by activating the potassium channels in the vasculature when used for this indication. But, when it comes to using Minoxidil for your hair, how does it provide the benefits that it does to your scalp and hair follicles?

However, we do know a few things that may be part of the story behind how Minoxidil works for hair growth.:  

1. Minoxidil may help increase the length of the hair cycle’s anagen (growth phase) by acting directly on the hair follicles as a growth factor. This may delay the ageing of some of the matrix cells of the hair follicles.  

2. Minoxidil may help limit some adverse androgen effects on androgen-sensitive hair. This is important when it comes to pattern hair loss, as the androgen DHT is the known culprit for the hair follicle damage that drives the shrinking and eventual loss of hair. 

3. Minoxidil applied topically to the scalp can help turn on the endoperoxide-synthase one pathway, which is known to stimulate hair growth.

4. Minoxidil is known to induce the expression of growth factors that cause the development of more vessels around the hair follicle area. This benefits hair growth as more vessels means more nutrients and oxygen readily available to the hair follicles. 

5. Minoxidil can stimulate the dilation of the existing microvessels surrounding the hair follicles, potentially leading to improved hair growth. 

6. Minoxidil has been found to increase intracellular calcium levels, which leads to the expression of more ATP synthase. This ATP synthase increase promotes stem cell differentiation which may be part of the reason behind Minoxidil’s hair growth functionality. 

Predicting potential response to Minoxidil:

 ‘Minoxidil Response DNA Test’ was developed to help determine how effective the topical drug may be for treating genetic hair loss individually with 7-14 days of turnaround time for results. It saves money and time. We are offering this critical Minoxidil Response DNA Test for a low price and affordable to everyone who takes minoxidil treatment for hair loss, said the founders of TrichoGene, INDIA. 

There is a common query – Will Minoxidil work if I’m bald?

Minoxidil is also unlikely to regrow hair on a completely bald scalp. Once male-pattern baldness has progressed to complete baldness, that suggests that your hair follicles are no longer functional and hair regrowth is not likely. Remember, Minoxidil encourages your hair follicle to grow—if the follicle is not functional anymore, there is not much for Minoxidil to work with.

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